A meeting of the minds to ensure your molecule’s safety.

Neurotoxicology Studies

We have a number of senior staff members who are active in the fast-moving field of neuroscience. We partner with you to develop, optimize and implement innovative techniques to evaluate the potential toxicity effects of your molecule on the nervous system.

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We offer a wide range of techniques for neurotoxicology assessment including:

  • EPA acute neurotoxicity battery
  • Subchronic neurotoxicity
  • Behavioral testing
  • Abuse liability
  • Seizure liability
  • Developmental neurotoxicity
  • Nerve conductance test
  • EthoVision™

Abuse liability. A crucial step if your molecule has a central nervous system effect.

Our team first evaluates the mechanism of action, pharmacokinetics data, and active metabolites, based on the target population. We then outline a study plan that provides all the necessary testing and documentation required for regulatory reporting. Specific services include:

  • Neuropharmacological characterization
  • Receptor binding
  • Animal behavioral data
  • Neurobehavioral effects
  • Discriminative effects
  • Reinforcing effects
  • Physical dependence
  • Tolerance

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